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Data regarding safety issues are not sufficiently available. PBM program included multiple measures ie, preoperative optimization of hemoglobin levels, blood-sparing techniques, and standardization of transfusion practice. Primary aim was to show noninferiority of the PBM cohort with a margin of 0.
Secondary endpoints included red blood cell utilization. A total of , patients discharged between July and June with different inclusion periods for pre-PBM 54, patients and PBM 75, patients were analyzed. The primary endpoint was 6. The noninferiority aim was achieved P cohort 2. To discuss how best to implement the gatekeeping functionality of primary care; identifying the factors that cause patients to bypass their primary care gatekeepers when seeking care should be beneficial.
To examine the association between patient experience with their primary care physicians and bypassing them to directly obtain care from higher-level healthcare facilities. This prospective cohort study was conducted in 13 primary care clinics in Japan.
We assessed patient experience of primary care using the Japanese version of Primary Care Assessment Tool JPCAT , which comprises six domains: first contact, longitudinality, coordination, comprehensiveness services available , comprehensiveness services provided , and community orientation. The primary outcome was the patient bypassing their usual primary care physician to seek care at a hospital, with this occurring at least once in a year. We used a Bayesian hierarchical model to adjust clustering within clinics and individual covariates.
Data were analyzed from patients for whom a physician at a clinic served as their usual primary care physician. The patient follow-up rate was After adjustment for patients' sociodemographic and health status characteristics, the JPCAT total score was found to be inversely associated with patient bypass behavior odds ratio per 1 SD increase, 0.
The results of various sensitivity analyses were consistent with those of the primary analysis. We found that patient experience of primary care in Japan was inversely associated with bypassing a primary care gatekeeper to seek care at higher-level healthcare facilities, such as hospitals.
Our findings suggest that primary care providers' efforts to improve patient experience should help to ensure appropriate use of healthcare services under loosely regulated gatekeeping systems; further studies are warranted. The effect of blood transfusion on pulmonary permeability in cardiac surgery patients: a prospective multicenter cohort study.
There is an association between blood transfusion and pulmonary complications in cardiac surgery. Mediators of increased pulmonary vascular leakage after transfusion are unknown. We hypothesized that factors may include antibodies or bioactive lipids, which have been implicated in transfusion-related acute lung injury. We performed a prospective cohort study in two university hospital intensive care units in the Netherlands.
The pulmonary leak index PLI , using 67 Ga-labeled transferrin, was determined within 3 hours postoperatively. Blood products were screened for bioactive lipid accumulation and the presence of antibodies. The PLI was elevated in all groups after cardiac surgery. Prospective cohort study. Five hospitals in the Netherlands and Belgium. Consecutive patients with BBS. Initial and long term clinical success, stent migration rate and safety.
Two patients died of an unrelated cause before stent removal, and no data on these patients were available on stricture resolution. Nonrandomized study design. The antimigration design could not prevent migration in a significant number of patients with a persisting stricture. Little is known about the physical symptoms and psychosocial burden of patients at the time of diagnosis of an incurable situation, although cancer treatment guidelines demand early assessment and integration of palliative care concepts, beginning from the diagnosis of incurability.
Therefore, we initiated a prospective longitudinal multicenter cohort study assessing the symptoms and needs of patients suffering from incurable cancer various entities , from the time of diagnosing incurability i. Here, we focus on patients with head and neck cancer and present preliminary results on symptoms and need prevalences, on clinical implications, and on the feasibility of a methodologically complex assessment procedure in a particularly vulnerable study population.
The Eastern Cooperative Oncology Group ECOG performance scores and most physical symptoms and psychosocial items varied between the extremes, from a virtually uncompromised condition to extremely perceived symptoms and needs. If intense face-to-face study support was provided, the study concept proved to be feasible, despite the complexity of assessment, problems in interdisciplinary and patient communication, comorbidities, and early death from complications.
The striking variability in the perceived symptom and need intensities requires a highly individualized approach. For clinical purposes, a less complex screening procedure would be desirable, in order to enable a routine, early and comprehensive support, including palliative care services.
Karger GmbH, Freiburg. Predictive validity of granulation tissue color measured by digital image analysis for deep pressure ulcer healing: a multicenter prospective cohort study. This multicenter prospective cohort study examined the predictive validity of granulation tissue color evaluated by digital image analysis for deep pressure ulcer healing. Ninety-one patients with deep pressure ulcers were followed for 3 weeks. From a wound photograph taken at baseline, an image representing the granulation red index GRI was processed in which a redder color represented higher values.
In the linear mixed model, higher classes for all GRI parameters showed significantly greater relative improvement in overall wound severity during the 3 weeks after adjustment for patient characteristics and wound locations. Assessment of granulation tissue color by digital image analysis will be useful as an objective monitoring tool for granulation tissue quality or surrogate outcomes of pressure ulcer healing. The impact of social engagement on health-related quality of life and depressive symptoms in old age - evidence from a multicenter prospective cohort study in Germany.
Thus far, only a few longitudinal studies investigated the impact of social engagement on health-related quality of life HRQoL and depressive symptoms in old age. Therefore, we aimed to examine the impact of social engagement on HRQoL and depressive symptoms in late life. Individuals reported the frequency "never" to "every day" of social engagement e. Fixed effects regressions were used to estimate the effect of social engagement on the outcome variables.
After adjusting for age, marital status, functional status and chronic diseases, fixed effects regressions revealed that the onset of social engagement markedly increased HRQoL and considerably decreased depressive symptoms in the total sample and in women, but not men. Our findings corroborate the relevance of social engagement for HRQoL and depressive symptoms in old age.
Encouraging the individuals to start, maintain and expand social engagement in late life might help to maintain and improve HRQoL and decrease depressive symptoms. Baseline data from a multicenter , 5-year, prospective cohort study of Japanese age-related macular degeneration: an AMD report.
To report research participants' baseline characteristics in the AMD study, a prospective , multicenter , 5-year, observational cohort study of Japanese age-related macular degeneration AMD. The characteristics were determined using multimodal imaging. Each patient underwent a complete ophthalmic examination, including measurement of best-corrected visual acuity Landolt chart , indirect ophthalmoscopy, slit-lamp biomicroscopy with a contact lens, optical coherence tomography imaging, fundus photography, and fluorescein and indocyanine green angiography.
Four hundred sixty participants men [ At enrollment, eyes A total of eyes Of the eyes with wet AMD, eyes Ischemia on computed tomography CT is associated with subsequent stroke after transient ischemic attack. This study assessed CT findings of acute ischemia, chronic ischemia, or microangiopathy for predicting subsequent stroke after transient ischemic attack.
This prospective cohort study enrolled patients with transient ischemic attack or nondisabling stroke that had CT scanning within 24 hours. Primary outcome was subsequent stroke within 90 days. CT findings were classified as ischemia present or absent and acute or chronic or microangiopathy. Analysis used Fisher exact test and multivariate logistic regression. A total of patients were included; had ischemic changes on CT. Subsequent stroke rate was 3.
Stroke risk was greater if baseline CT showed acute ischemia alone Logistic regression found acute ischemia alone odds ratio [OR], 2. Only acute ischemia OR, 2. Salivary pathogen and serum antibody to assess the progression of chronic periodontitis: a mo prospective multicenter cohort study. A diagnosis of periodontitis progression is presently limited to clinical parameters such as attachment loss and radiographic imaging.
The aim of this multicenter study was to monitor disease progression in patients with chronic periodontitis during a mo follow-up program and to evaluate the amount of bacteria in saliva and corresponding IgG titers in serum for determining the diagnostic usefulness of each in indicating disease progression and stability.
A total of patients with chronic periodontitis who received trimonthly follow-up care were observed for 24 mo. The changes through 24 mo were analyzed using cut-off values calculated for each factor. Diagnostic values were calculated using Fisher's exact test. Of the individuals who completed the mo monitoring phase, 62 exhibited periodontitis progression, whereas 62 demonstrated stable disease.
Seven patients withdrew because of acute periodontal abscess. The ratio of P. The combination of P. It is suggested that the combination of P. Pre-fracture nutritional status is predictive of functional status at discharge during the acute phase with hip fracture patients: A multicenter prospective cohort study. Malnutrition is common in patients with hip fractures, and elderly patients with hip fractures lose functional independence and often fail to recover previous functional status.
The aim of this study was to determine whether pre-fracture nutritional status predicts functional status of patients with hip fracture at discharge from acute hospitals. At discharge from acute hospitals, functional status was evaluated using a functional independent measurement instrument FIM.
Among the patients analyzed in the present study, the mean length of hospital stay was Retrospective analysis of a prospective , multicenter cohort study. To estimate the added effect of surgical fusion as compared to decompression surgery alone in symptomatic lumbar spinal stenosis patients with spondylolisthesis. The optimal surgical management of lumbar spinal stenosis patients with spondylolisthesis remains controversial.
The outcomes of this study were Spinal Stenosis Measure SSM symptoms score range , best-worst and function over time, measured at baseline, 6, 12, 24, and 36 months follow-up. In order to quantify the effect of fusion surgery as compared to decompression alone and number of decompressed levels, we used mixed effects models and accounted for the repeated observations in main outcomes SSM symptoms and SSM function over time.
In addition to individual patients' random effects, we also fitted random slopes for follow-up time points and compared these two approaches with Akaike's Information Criterion and the chi-square test. Confounders were adjusted with fixed effects for age, sex, body mass index, diabetes, Cumulative Illness Rating Scale musculoskeletal disorders, and duration of symptoms.
In the multiple mixed effects model the adjusted effect of fusion compared with decompression alone surgery on SSM symptoms was 0. Among the patients with degenerative lumbar spinal stenosis and spondylolisthesis our study confirms that in the two groups, decompression alone and decompression with fusion, patients distinctively benefited from surgical treatment.
When adjusted for confounders, fusion surgery was not associated with a more. Distraction arthrodesis of the sacroiliac joint: 2-year results of a descriptive prospective multi-center cohort study in patients. The aim of the given study was to evaluate the long-term outcomes of patients undergoing sacroiliac joint SIJ distraction arthrodesis to treat SIJ-related pain.
Descriptive prospective multi-center cohort study involving 20 hospitals in Germany. The patients were questioned prior to surgery, 6-weeks, and 3-, 6-, and months postoperatively. A prospective multicenter cohort study. To investigate whether the incidence of pressure ulcers in nursing homes in the Netherlands and Germany differs and, if so, to identify resident-related risk factors, nursing-related interventions, and structural factors associated with pressure ulcer development in nursing home residents.
Ten nursing homes in the Netherlands and 11 nursing homes in Germany around Berlin and Brandenburg. A total of newly admitted nursing home residents, of which were Dutch and were German. Residents had an expected length of stay of 12 weeks or longer.
Data were collected for each resident over a week period and included resident characteristics eg, demographics, medical history, Braden scale scores, nutritional factors , pressure ulcer prevention and treatment characteristics, staffing ratios and other structural nursing home characteristics, and outcome pressure ulcer development during the study. Data were obtained by trained research assistants.
A significantly higher pressure ulcer incidence rate was found for the Dutch nursing homes Six factors that explain the difference in pressure ulcer incidence rates were identified: dementia, analgesics use, the use of transfer aids, repositioning the residents, the availability of a tissue viability nurse on the ward, and regular internal quality controls in the nursing home. The pressure ulcer incidence was significantly higher in Dutch nursing homes than in German nursing homes.
Factors related to residents, nursing care and structure explain this difference in incidence rates. Continuous attention to pressure ulcer care is important for all health care settings and countries, but Dutch nursing homes especially should pay more attention to repositioning residents, the necessity and correct use of transfer aids, the necessity of analgesics use, the tasks of the tissue viability nurse, and the performance of regular.
ABSTRACT Staphylococcus aureus is an important pathogen causing a spectrum of diseases ranging from mild skin and soft tissue infections to life-threatening conditions. Bloodstream infections are particularly important, and the treatment approach is complicated by the presence of methicillin-resistant S. Here, we prospectively characterized bloodstream MRSA recovered from selected hospitals in 9 Latin American countries.
All isolates were typed by pulsed-field gel electrophoresis PFGE and subjected to antibiotic susceptibility testing. Whole-genome sequencing was performed on 96 MRSA representatives. Phylogenetic reconstructions indicated that MRSA isolates from participating hospitals belonged to three major clades. Clonal replacement appears to be a common phenomenon, and continuous surveillance is crucial to identify changes in the molecular epidemiology of MRSA. Staphylococcus aureus is an important pathogen causing a spectrum of diseases ranging from mild skin and soft tissue infections to life-threatening conditions.
Psychometric properties of the m walking test in patients with degenerative cervical myelopathy: results from two prospective multicenter cohort studies. The timed m walking test 30MWT is used in clinical practice and in research to objectively quantify gait impairment.
The psychometric properties of 30MWT have not yet been rigorously evaluated. This study aimed to determine test-retest reliability, divergent and convergent validity, and responsiveness to change of the 30MWT in patients with degenerative cervical myelopathy DCM. A retrospective observational study was carried out. Data from two prospective multicenter cohort myelopathy studies were merged.
Each patient was evaluated at baseline and 6 months postoperatively. Of total patients, Of these patients, One patient was excluded, leaving in the analysis. At baseline, 81 of The 30MWT demonstrated good convergent and divergent validity. However, for patients who had a baseline time above the median value of 29 seconds, the SRM was 0.
The 30MWT. To analyze how well untrained examiners - without experience in the use of International Ovarian Tumor Analysis IOTA terminology or simple ultrasound-based rules simple rules - are able to apply IOTA terminology and simple rules and to assess the level of agreement between non-experts and an expert. This prospective multicenter cohort study enrolled women with ovarian masses. Ultrasound was performed by non-expert examiners and an expert.
Ultrasound features were recorded using IOTA nomenclature, and used for classifying the mass by simple rules. We observed 46 discrepancies in the description of ovarian masses when non-experts utilized IOTA terminology.
The level of agreement for all 10 simple rules features varied greatly kappa index range: Although simple rules are useful to distinguish benign from malignant adnexal masses, they are not that simple for untrained examiners. Training with both IOTA terminology and simple rules is necessary before simple rules can be introduced into guidelines and daily clinical practice.
The association of HIV with coronary atherosclerosis has been established; however, the progression of coronary atherosclerosis over time among participants with HIV is not well known. We measured coronary plaque volume and characteristics calcified and noncalcified plaque including fibrous, fibrous-fatty, and low attenuation and vulnerable plaque among HIV-infected and uninfected men using semiautomated plaque software to investigate the progression of coronary atherosclerosis over time.
We describe a novel, large prospective multicenter study investigating incidence, transition of characteristics, and progression in coronary atherosclerosis quantitatively assessed by serial coronary CTAs among HIV-infected and uninfected men. Cost savings associated with prevention of recurrent lumbar disc herniation with a novel annular closure device: a multicenter prospective cohort study.
Same-level recurrent disc herniation is a well-defined complication following lumbar discectomy. Reherniation results in increased morbidity and health care costs. Techniques to reduce these consequences may improve outcomes and reduce cost after lumbar discectomy. In a prospective cohort study, we set out to evaluate the cost associated with surgical management of recurrent, same-level lumbar disc herniation following primary discectomy. Forty-six consecutive European patients undergoing lumbar discectomy for a single-level herniated disc at two institutions were prospectively followed with clinical and radiographic evaluations.
A second consecutive cohort of 30 patients undergoing 31 lumbar discectomies with implantation of an annular closure device was followed at the same hospitals and same follow-up intervals. Cost estimates for reherniation were modeled on Medicare national allowable payment amounts direct cost and patient work-day losses indirect cost. Annular closure and control cohorts were matched at baseline.
By 2 years follow-up, symptomatic recurrent same-level disc herniation occurred in three 6. Medicare costs. Recurrent disc herniation did not occur in any patients after annular closure within the month follow-up. The reduction in the incidence of reherniation was associated with potentially significant cost savings.
Development of novel techniques to prevent recurrent lumbar disc herniation is warranted to decrease the associated morbidity and. Prospective national multicenter study. Level 1 trauma centers in Norway. Functional recovery between 3 and 12 months postinjury measured with Glasgow Outcome Scale Extended, Rivermead Postconcussion Symptoms Questionnaire, Hospital Anxiety and Depression Scale, and satisfaction with life situation.
Despite the generally increased risk of bone fractures among patients with end-stage renal disease, no prediction models for identifying individuals at particular risk have been developed to date. An open prospective single cohort multicenter study evaluating the novel, tapered, conical connection implants supporting single crowns in the anterior and premolar maxilla: interim 1-year results.
The aim of this multicenter prospective clinical study was to evaluate anodized tapered implants with a conical connection and integrated platform shifting placed in the anterior and premolar maxilla. The study enrolled patients requiring single-tooth restorations in healed sites of maxillary anterior and premolar teeth.
All implants were immediately temporized. Outcome measures included bone remodeling, cumulative survival rate CSR , success rate, soft-tissue health and esthetics, and patient satisfaction. Bone remodeling and pink esthetic score were analyzed using Wilcoxon signed-rank tests. CSR was calculated using life table analysis. Other soft-tissue outcomes were analyzed using sign tests. Out of 97 enrolled patients implants , 87 patients 91 implants completed the 1-year visit.
Marginal bone remodeling was After the expected initial bone loss, a mean bone gain of 0. The CSR was Partial or full papilla was observed at Soft-tissue response, esthetics, and patient satisfaction all improved during the study period. Bone gain was observed following the expected initial bone loss, and soft-tissue outcomes improved suggesting favorable tissue response using anodized tapered conical connection implants. Rapid stabilization of bone remodeling and robust papilla regeneration indicate favorable tissue healing promoted by the conical connection, platform-shift design.
Immediate provisionalization in the esthetic zone: 1-year interim results from a prospective single- cohort multicenter study evaluating 3. The aim of this interim analysis of a 5-year prospective multicenter study is to evaluate clinical and radiological performance of immediately provisionalized 3. Patients needing implant rehabilitation of maxillary lateral incisors or mandibular lateral and central incisors were treated with 3.
Marginal bone levels and changes, complications, the papilla, plaque, and bleeding indices, and the pink esthetic score PES were evaluated at each follow-up visit. Of enrolled patients, 77 patients 91 implants met the inclusion criteria. Seventy-one patients with 82 implants completed the 1-year follow-up. Three implants failed yielding a CSR of Fifteen non-serious complications were recorded. Papilla index score and PES improved at the 1-year follow-up.
Plaque formation and bleeding-on-probing showed no statistically significant differences between the 6-month and the 1-year visit. This 1-year analysis demonstrated high survival, stable bone levels, and healthy soft tissue with 3. Cytomegalovirus infections in lung and hematopoietic cell transplant recipients in the Organ Transplant Infection Prevention and Detection Study: A multi-year, multicenter prospective cohort study.
Most studies of post-transplant CMV infection have focused on either solid organ or hematopoietic cell transplant HCT recipients. A large prospective cohort study involving both lung and HCT recipients provided an opportunity to compare the epidemiology and outcomes of CMV infections in these 2 groups. Data on demographics, CMV infections, tissue-invasive disease, recurrences, rejection, and immunosuppression were recorded. Background Revision anterior cruciate ligament ACL reconstruction has worse outcomes than primary reconstructions.
Predictors for these worse outcomes are not known. The Multicenter ACL Revision Study MARS Group was developed to perform a multisurgeon, multicenter prospective longitudinal study to obtain sufficient subjects to allow multivariable analysis to determine predictors of clinical outcome. Purpose To describe the formation of MARS and provide descriptive analysis of patient demographics and clinical features for the initial enrolled patients to date in this prospective cohort.
Study Design Cross-sectional study; Level of evidence, 2. Methods After training and institutional review board approval, surgeons began enrolling patients undergoing revision ACL reconstruction, recording patient demographics, previous ACL reconstruction methods, intra-articular injuries, and current revision techniques. Enrolled subjects completed a questionnaire consisting of validated patient-based outcome measures. Traumatic reinjury is deemed by surgeons to be the most common single mode of failure, but a combination of factors represents the most.
Chinese cancer patients often use Traditional Chinese Medicine TCM herbal medicine during or after active cancer treatments. However, little is known about how TCM herbal medicine impacts cancer outcomes. We conducted an eight-center prospective cohort study in China among patients who had undergone radical resection for stage II and III colorectal cancer. All patients received comprehensive conventional treatments according to National Comprehensive Cancer Network NCCN guidelines, and follow-up visits were conducted over five years.
We defined high exposure as a patient's use of TCM individualized herbs for more than one year, ascertained via clinical interviews. Between April and February , we enrolled patients into the cohort ; In subgroup exploratory analysis, the effects demonstrated that the differences in outcomes were statistically significant in patients who had received chemotherapy. More research is needed to evaluate the effects and underlying mechanisms of herbal medicine on colorectal cancer outcomes.
Published by Oxford University Press. For Permissions, please e-mail: journals. Interim analysis of survival in a prospective , multi-center registry cohort of cutaneous melanoma tested with a prognostic gene expression profile test. A gene expression profile GEP test that provides risk classification of cutaneous melanoma CM patients has been validated in several retrospective studies.
The objective of the reported study was a prospective evaluation of the GEP performance in patients enrolled in two clinical registries. Median follow-up was 1. RFS outcomes in this real-world cohort are consistent with previously published analyses with retrospective specimens. GEP testing complements current clinicopathologic features and increases identification of high-risk patients.
A belgian multicenter prospective observational cohort study shows safe and efficient use of a composite mesh with incorporated oxidized regenerated cellulose in laparoscopic ventral hernia repair. A variety of anti-adhesive composite mesh products have become available to use inside the peritoneal cavity. There were no conversions to open repair, no enterotomies, no mesh infections and no mortality. Quality of life could not be analyzed due to incomplete data set.
More than 5 years after introduction of this mesh to the market, this prospective multicentric study documents a favorable experience with the Proceed mesh in laparoscopic ventral hernia repair. However, it remains to be discussed whether reimbursement of these meshes in Belgium should be limited to the current strict criteria and therefore can only be obtained after at least years of clinical data gathering and necessary follow-up.
Highly elevated serum lactate dehydrogenase is associated with central nervous system relapse in patients with diffuse large B-cell lymphoma: Results of a multicenter prospective cohort study. Central nervous system involvement remains a challenging issue in the treatment of patients with diffuse large B-cell lymphoma. We conducted a prospective cohort study with newly diagnosed diffuse large B-cell lymphoma patients receiving rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone to identify incidence and risk factors for central nervous system involvement.
Among patients, patients received pre-treatment central nervous system evaluation, and 14 patients had central nervous system involvement at diagnosis 2. For those patients, median follow-up duration was Out of patients who did not have central nervous system involvement at diagnosis, 26 patients underwent secondary central nervous system relapse with a median follow-up of 35 months, and the median time to central nervous system involvement was Our study suggests that enhanced stratification of serum lactate dehydrogenase according to the National Comprehensive Cancer Network-International Prognostic Index may contribute to better prediction for central nervous system relapse in patients with diffuse large B-cell lymphoma.
This trial was registered at clinicaltrials. The primary tumor and up to 3 additional lesions per patient were analyzed. The repeatability of each metric was assessed by Bland-Altman analysis. Results: One hundred and five lesions primary tumors and nodal or distant metastases were delineated and characterized.
Several shape and heterogeneity features were found to be highly or moderately repeatable e. Conclusion: Our results in this large multicenter cohort with more than measurements confirm the PET findings in previous studies with Acute kidney injury is a powerful independent predictor of mortality in critically ill patients: a multicenter prospective cohort study from Kinshasa, the Democratic Republic of Congo.
Despite the growing incidence of acute kidney injury AKI worldwide, there is little data on the burden and outcomes of AKI in intensive care unit ICU in low resource settings. The primary outcome was 28 days mortality. Survival time-to death curves were built using the Kaplan Meier methods.
Predictors of mortality were assessed by Cox proportional hazards regression models. Quality of oral anticoagulation with phenprocoumon in regular medical care and its potential for improvement in a telemedicine-based coagulation service--results from the prospective , multi-center , observational cohort study thrombEVAL. The majority of studies on quality of oral anticoagulation OAC therapy with vitamin K-antagonists are performed with short-acting warfarin.
Data on long-acting phenprocoumon, which is frequently used in Europe for OAC therapy and is considered to enable more stable therapy adjustment, are scarce. In this study, we aimed to assess quality of OAC therapy with phenprocoumon in regular medical care and to evaluate its potential for optimization in a telemedicine-based coagulation service.
In the prospective observational cohort study program thrombEVAL we investigated 2, patients from regular medical care in a multi-center cohort study and patients from a telemedicine-based coagulation service in a single-center cohort study. Data were obtained from self-reported data, computer-assisted personal interviews, and laboratory measurements according to standard operating procedures with detailed quality control.
Study monitoring was carried out by an independent institution. Overall, 15, treatment years and 48, international normalized ratio INR measurements were analyzed. Quality of anticoagulation, as measured by median TTR, was This postauthorization study assessed the incidence and intensity of cardiovascular events, including ischemic stroke, in patients receiving epoetin theta for anemia associated with CKD. A secondary end point was adverse drug reactions, including pure red cell aplasia.
In this prospective , noninterventional, multinational cohort study, consecutive patients with advanced or end-stage renal disease and receiving epoetin theta were followed up for 6 months. Data on reportable adverse events RAEs cardiac disorders, cardiac failure, myocardial infarction, and ischemic stroke and respective subterms , epoetin theta dosage, and Hb concentrations were collected.
Data from patients were included men, women; mean age, A total of RAEs were documented in 89 patients 8. Sixty-four patients 6. The incidence of RAEs was lowest at intermediate Hb concentrations 6. The incidence of ischemic stroke was 1. The incidence of any RAE was greater in the high-dose group In this study, the results of a multicenter long-term survey are presented.
TM was bilateral in TM remained unchanged at 4. Orchiectomy was performed in three patients 3. Tumorectomy with parenchymal sparing surgery was performed in a teratoma associated with TM. Testicular malignancy, although present in TM, has not proven definitively associated to microliths. Proper counseling, yearly ultrasound, and self-examination are long-term recommended. To determine prognostic factors of clinically relevant radiographic progression CRRP in patients with rheumatoid arthritis RA in clinical practice.
We longitudinally observed patients for 1 year and assessed disease activity every 3 months. We also divided the cohort into 2 groups based on disease duration A 5-year multicenter prospective cohort study on the long-term visual prognosis and predictive factors for visual outcome in Japanese patients with age-related macular degeneration: the AMD study.
This was a multicenter prospective observational cohort study. They were followed up for 5 years, as they continued to receive medical treatment. Of the study eyes followed up for at least 1 year, eyes Bosentan reduces pulmonary arterial pressure and improves exercise capacity in patients with pulmonary arterial hypertension PAH. However, there are limited data regarding the extent to which the changes in echocardiographic variables reflect improvements in exercise capacity.
We aimed to assess the improvement of echocardiographic variables and exercise capacity after 6 months of bosentan treatment for PAH. We performed a prospective study from June to June in seven participating medical centers. Echocardiography, including tissue Doppler imaging TDI and the 6-minute walk test distance 6MWD , was performed at baseline and after 6 months of bosentan treatment.
We analyzed 19 patients with PAH: seven with congenital shunt, six with collagen vascular disease, and six with idiopathic PAH. After bosentan treatment, mean 6MWD increased by 50 meters. J Clin Ultrasound , Apixaban, one of the non-vitamin K antagonist oral anticoagulants, was reported to be effective and safe in stroke prevention in patients with atrial fibrillation AF based on the global randomized clinical trial, but data are limited on the efficacy and safety of apixaban in Japanese elderly patients.
The J-ELD AF Registry is a large-scale, contemporary observational study, continuously and prospectively registering elderly Japanese patients with AF aged 75 years or older who are currently taking apixaban or the elderly who are to receive apixaban in daily clinical practice, and accumulating the outcomes during one-year follow-up period.
In addition to standard baseline characteristics, prothrombin time and anti-Xa activity will be measured to investigate the biomarker characteristics. The primary efficacy endpoints will be stroke and systemic embolism, and the primary safety endpoint will be major bleeding requiring hospitalization. This study will provide important information on the efficacy and safety of apixaban in elderly Japanese patients aged 75 years or older, and those of low-dose administration of apixaban 2.
Published by Elsevier Ltd. All rights. Outcomes after unrestricted use of everolimus-eluting and sirolimus-eluting stents in routine clinical practice: a multicenter , prospective cohort study. It remains unclear whether there are differences in the safety and efficacy outcomes between everolimus-eluting stents EES and sirolimus-eluting stents SES in contemporary practice.
The primary end point was a composite of death, nonfatal myocardial infarction MI , or target-vessel revascularization TVR. At 2 years of follow-up, the 2 study groups did not differ significantly in crude risk of the primary end point After adjustment for differences in baseline risk factors, the adjusted risk for the primary end point remained similar for the 2 stent types HR, 0.
There were also no differences between the stent groups in the adjusted risks of the individual component of death HR, 0. The adjusted risk of stent thrombosis also was similar HR, 1. In contemporary practice of percutaneous coronary intervention procedures, the unrestricted use of EES and SES showed similar rates of safety and efficacy outcomes with regard to death, MI, sent thrombosis, and TVR.
Future longer-term follow-up is needed to better define the relative benefits of these drug-eluting stents. Unique identifier: NCT Chest computed tomography CT diagnoses more injuries than chest radiography, so-called occult injuries. Wide availability of chest CT has driven substantial increase in emergency department use, although the incidence and clinical significance of chest CT findings have not been fully described.
We determine the frequency, severity, and clinical import of occult injury, as determined by changes in management. These data will better inform clinical decisions, need for chest CT, and odds of intervention. Our sample included prospective data to on 5, patients at 10 Level I trauma center EDs with both chest radiography and chest CT at physician discretion.
These patients were Occult injuries were pneumothorax, hemothorax, sternal or greater than 2 rib fractures, pulmonary contusion, thoracic spine or scapula fracture, and diaphragm or great vessel injury found on chest CT but not on preceding chest radiography. Primary outcome was prevalence and proportion of occult injury with major interventions of chest tube, mechanical ventilation, or surgery. Secondary outcome was minor interventions of admission rate or observation hours because of occult injury.
Two thousand forty-eight patients Of these, in patients In more patients Chest radiography found all injuries in only Two hundred and two. The Neuropsychological NP substudy was begun in following reports of significant adverse neurological consequences of HIV disease, including dementia.
The goal was to characterize the neuropsychological deficits among individuals with HIV disease, and track the natural history of the neurological complications over time. Initially, a subcohort was evaluated semi-annually with NP tests but, beginning in , the entire group of MACS participants have had NP examinations biannually, unless closer follow-up was warranted. Additional behavioural data, including mood state and psychoactive substance use, are recorded as part of the main MACS data collection.
Beginning in October , the PDS has been released annually with new releases superseding previous versions. Delayed antifungal therapy for invasive candidiasis IC contributes to poor outcomes. Predictive risk models may allow targeted antifungal prophylaxis to those at greatest risk. From these parameters, a risk-predictive model for the development of ICU-acquired IC was then derived.
Ninety-six patients 1. No single threshold score could categorize patients into clinically useful high- and low-risk groups. Categorizing patients into high-, intermediate-, and low-risk groups may more efficiently target early antifungal strategies and utilization of newer diagnostic tests.
For permissions, e-mail journals. It has been validated retrospectively in a single center in South Korea. We aimed to validate the OPS prospectively for advanced cancer inpatients in South Korea using a multicenter study. This was a prospective cohort study. We enrolled advanced cancer patients admitted in five palliative care units in South Korea from May till March Seven members of the Korean Palliative Medicine Research Network who are experts of palliative care led the study.
Survival time was calculated as days from enrollment to death during admission. A total of patients were included in the final analysis feasibility: It is a useful method to predict three-week survival of Korean inpatients with advanced cancer. Clinical validity of the estimated energy requirement and the average protein requirement for nutritional status change and wound healing in older patients with pressure ulcers: A multicenter prospective cohort study.
Adequate nutritional intake is essential for pressure ulcer healing. The purpose was to evaluate the clinical validity of these requirements in older hospitalized patients with pressure ulcers by assessing nutritional status and wound healing. Energy and protein intake were determined from medical records on a typical day and dichotomized by meeting the estimated average requirement.
Longitudinal data were analyzed with a multivariate mixed-effects model. Parkinson's disease PD is a progressive neurodegenerative disorder causing motor and non-motor symptoms that can affect independence, social adjustment and the quality of life QoL of both patients and caregivers. Observational, descriptive, non-interventional, 5-year follow-up, national Spain , multicenter 45 centers from 15 autonomous communities , evaluation study.
Specific goals: 1 detailed study clinical evaluations, serum biomarkers, genetic studies and neuroimaging of a population of PD patients from different areas of Spain, 2 comparison with a control group and 3 follow-up for 5 years. Study evaluations: 1 baseline includes motor assessment e. Technical success from endovascular aneurysm repair in the post-marketing era: a multicenter prospective trial.
Evaluation of post-marketing success with the Ancure Endovascular Graft AEG was accomplished by review of a multicenter , prospective trial involving 46 centers and patients. Technical success in both groups of patients One of four patients undergoing conversion in the prospective trial had graft misdeployment as a mode of failure. Three were converted for access failure.
The day mortality rate in the prospective trial was 3. Interventions to resolve implantation-related events included stenting, guide catheter manipulations, wire exchanges, and delivery catheter disassembly. These interventions were successful in virtually every case. Open surgical procedures were not needed to correct these operative problems. Results from this study demonstrate excellent technical success with the AEG in the post-market era. Interventions to resolve implantation complications, when utilized, are highly successful in facilitating AEG implantation and providing technical success.
There is a pressing need for robust longitudinal cohort studies in the modern treatment era of multiple sclerosis. Build a multiple sclerosis MS cohort repository to capture the variability of disability accumulation, as well as provide the depth of characterization clinical, radiologic, genetic, biospecimens required to adequately model and ultimately predict a patient's course.
We provide evidence for harmonization of two of the initial cohorts in terms of the characterization of demographics, disease, and treatment-related variables; demonstrate several proof-of-principle analyses examining genetic and radiologic predictors of disease progression; and discuss the steps involved in expanding SUMMIT into a repository accessible to the broader scientific community.
Isolated optic nerve gliomas: a multicenter historical cohort study. Due to the rarity of this condition and the difficulty in differentiating IONGs from other types of OPGs in most clinical series, little is known about these tumors. Currently, due to lack of evidence, they are managed the same as any other OPG.
At least 1 year of follow-up, 2 MRI studies, and 2 neuro-ophthalmological examinations were required for inclusion. Age at diagnosis ranged between 6 months and 16 years average 6 years. The mean follow-up time was 5. Twenty-five patients had neurofibromatosis Type 1.
Nine patients were treated with chemotherapy, 5 of whom improved visually. Ten patients underwent operation, and no local or distal recurrence was noted. Radiological progression and visual deterioration occur in greater percentages than in the general population of patients with OPGs. Response to chemotherapy may be better in this group, and its use should be considered early in the course of the disease.
Febrile urinary tract infection after pediatric kidney transplantation: a multicenter , prospective observational study. Febrile urinary tract infections fUTIs are common after kidney transplantation KTx ; however, prospective data in a multicenter pediatric cohort are lacking.
Posttransplant, First fUTI posttransplant occurred earlier in boys compared with girls: median range 4 vs. Graft function worsened p prospective study confirms a high incidence of fUTI after pediatric KTx, which is not restricted to patients with CAKUT; fUTIs have a negative impact on graft function during the infectious episode but not on 2-year graft outcome.
Funding for graduate medical education is at risk despite the services provided by residents. We quantified the potential monetary value of services provided by on-call orthopedic surgery residents. We conducted a prospective , cross-sectional, multicenter cohort study design. Over a day period in , we collected data on consults by on-call orthopedic surgery residents at 4 tertiary academic medical centers in the United States. All inpatient and emergency department consults evaluated by first-call residents during the study period were eligible for inclusion.
Based on their current procedural terminology codes, procedures and evaluations for each consult were assigned a relative value unit and converted into a monetary value to determine the value of services provided by residents. The primary outcome measures were the total dollar value of each consult and the percentage of resident salaries that could be funded by the generated value of the resident consult services.
In total, consults seen by 33 residents from the 4 institutions were included for analysis. The potential monetary value generated by on-call orthopedic surgery residents is substantial. Cushing's syndrome CS is challenging to diagnose. Increased prevalence of CS in specific patient populations has been reported, but routine screening for CS remains questionable.
To decrease the diagnostic delay and improve disease outcomes, simple new screening methods for CS in at-risk populations are needed. To develop and validate a simple scoring system to predict CS based on clinical signs and an easy-to-use biochemical test. Observational, prospective , multicenter. Referral hospital. A cohort of patients attending endocrinology units for outpatient visits. All patients were evaluated with late-night salivary cortisol LNSC and a low-dose dexamethasone suppression test for CS.
Diagnosis or exclusion of CS. Twenty-six cases of CS were diagnosed in the cohort. A risk scoring system was developed by logistic regression analysis, and cutoff values were derived from a receiver operating characteristic curve. This risk score included clinical signs and symptoms muscular atrophy, osteoporosis, and dorsocervical fat pad and LNSC levels.
The estimated area under the receiver operating characteristic curve was 0. We developed a risk score to predict CS in an at-risk population. This score may help to identify at-risk patients in non-endocrinological settings such as primary care, but external validation is warranted. Seizures in juvenile Huntington's disease: frequency and characterization in a multicenter cohort.
Little is known about the epilepsy that often occurs in the juvenile form of Huntington's disease HD , but is absent from the adult-onset form. The primary aim of this study was to characterize the seizures in juvenile HD JHD subjects with regard to frequency, semiology, defining EEG characteristics, and response to antiepileptic agents. Data on age of HD onset, primary HD manifestations, number of CAG repeats, the presence or absence of seizures, seizure type s , antiepileptic drugs used, subjects' response to antiepileptic drugs AEDs , and EEG results were assembled, where available.
Ninety subjects with genetically confirmed JHD were included. Generalized tonic-clonic seizures were the most common seizure type, followed by tonic, myoclonic, and staring spells. Multiple seizure types commonly occurred within the same individual. Our ability to draw firm conclusions about defining EEG characteristics and response to AEDs was limited by the retrospective nature of the study. Future prospective studies are required.
Effectiveness of adjuvant radiotherapy in patients with oropharyngeal and floor of mouth squamous cell carcinoma and concomitant histological verification of singular ipsilateral cervical lymph node metastasis pN1-state - A prospective multicenter randomized controlled clinical trial using a comprehensive cohort design.
Background Modern radiotherapy plays an important role in therapy of advanced head and neck carcinomas. However, no clinical studies have been published addressing the effectiveness of postoperative radiotherapy in patients with small tumor pT1, pT2 and concomitant ipsilateral metastasis of a single lymph node pN1 , which would provide a basis for a general treatment recommendation.
As the primary clinical endpoint, overall-survival in patients receiving postoperative radiation therapy vs. This observational part of the trial will be performed with maximum consistency to the treatment and observation protocol of the RCT. Because the impact of patient preference for a certain treatment option is not calculable, parallel design of RCT and observational study may provide a maximum of evidence and efficacy for evaluation of treatment outcome.
All tumors represent a homogeneous clinical state and therefore additional investigation of protein expression levels within resection specimen may serve for establishment of. Karen Lansky Dr. Mary Lou Larson Dr. Nellie Lawson Dr. Susan Lee Mr. Mildred Lehnert Mr. John, Sr. Patricia Lenz Mr. Patricia Linck Mrs. Cheryl Lingle Mr. Ruth Longman Mr. Kaye Looney Ms. Judi Lotter Mr. John E. Lynne Lichtenauer Mr. Susan Lyons Dr. Jean Lytle Ms. Norine Maloney Mr.
Therese Manderino Mr. Marian Marinari Mr. Frank Marsaglia Mr. Pamela Martyn-Nemeth Mr. Gregory M. Brad McFaul Mr. Mickey McKee Mr. Julie McKune Drs. Peter McMenamin Mrs. Valerie Meaney Mr. Tracy Mikalauski Mr. Brad Miller Mr. James Montanari Mr. Diane Morefield Mr. Lorraine Morrey Dr. Margaret Moses Mr. James, USN Ret. Catherine Munsterman Mr. Thomas Murphy Mr.
Marianne Nelsen Mr. David Nelson Mr. Marilyn Nelson Mr. Amanda Nichols Ms. Melanie Obispo-Young Mr. Kim Pacholski Mr. Jean Palm Mr. Paul Palmer Ms. Kimberly Perona Mr. Joseph Petrosko, Jr. Susan Peyla Mrs. Joanne A. Porazinski Mr. Patricia Pratapas Ms. Peggy Pratl Reverend Richard B.
Prodehl Mr. Richard, Jr. Angela Reed Ms. Barbara M. Reidy Mr. Mary Reilly Professor Ellen T. Jennifer Rigley Ms. Judith Rollins Mrs. Meredith Rose Mr. Rita Ruddy Mr. Deena Rush Mr. Constance Russell Mr. Laurie Ryan Mr. Eileen Schackmuth Mr. Barbara Schwartz Mr. Margaret Sepsey Mr. Rita Sexton Mr. Lorelee Smith Mr. James M. Edmond A. Rosemary Stephen Mr.
John D. Doris Szczepaniak Mr. Mary Elizabeth Tallon Dr. Marilyn Tarizzo Mr. Ellen Taylor Mr. Robert Jr. Inez Thayer Mr. Rose Thomas Mr. Pamela Thomas Mr. Barbara Thompson Ms. Lynn Tovar Mr. Derek Tresnak Mr. Karen Tyler Dr. Nancy Vahl Mr. Valerie Vander Vliet Mr. Frank A. Beverly Voyce Mr.
Rosemary Wagner Mr. Suzanne Wielgos Mr. Mary Williams Mr. Susan Wolfram Mr. Nancy Workman Mr. Elizabeth Wroblewski Mr. Jion Liou Yen Mr. Brett Zbikowski Mr. Volleyball, Inc. National Seed Co. Next Media Operating Inc.
Mary Adams Dr. Glenna Adamson Mr. Ester Adomako Mrs. Lori Althoff Mr. Cheryl Alton Mr. Marylin Anderson Mrs. Cynthia Andres Mrs. Karen Applehoff Mr. Sheila Arends Mr. Lawrence Avila Mr. Ana Ayala Mr. Mary Ayer Mr. Jeff E. Balser Mr. Carolyn Bartelt Mr. Jo Barton Mr. Edward Batis Ms. Sandra Beal Ms. Sarah M. Wossenyelesh Gugsa Mr.
Janice Beneveti Mr. Jackie Benoit Mr. Karen Berta Mrs. Barbara Bertino Mr. Jon Bertino Mr. Christine Biedron Mr. Bernadette Bilder Mr. Kathleen Bilich Mr. Judith Billich Mr. Patricia Biscardi Mr. Lisa Bisgard Mr. Kathryn Bishop Mr. Sheryl Bixler Mr.
Katherine Blackburn Mr. Siri Blake Mr. Patti Block Mr. Joan Bodden Mr. Ronald Boehm 16 Mr. Darius Bolling Mr. Lillian Borse Mr. Marie Bosley Mr. John R. Bradley Mr. Regina Brett Mr. Lyndean Brick Mr. Judy Briesch Mr. Daniela Broderick Mr. John Brom Ms. Sarah Bromberek Mr. Phillip Brooks Mr. Patrick A. Doris Brozik Ms. Jenna M. Michael R. Judith C. Al Bucci Mr. Gina Buck Mr. George T. Bullock Mr. Lucy Burke Mr. David Burkhart Ms.
Mary J. Burns Mr. Laura Butkovic Ms. Jane Cain Mr. Nadine Caldwell Mr. Ann Cale Mrs. Debra M. Susan Calvert Mr. Jennifer Campagna Mr. Ryan P. Louise Canterbury Mr. Mary Capouch Mr. Loretta Capouch Mr. Mary Kay Cappitelli Mr. Lee Ann Cardwell Mr. Lisa Carey Mr. Louise Caridine Mr. Christine M. Christine Catena Mr.
Loretta Cernugel Mr. Kathy Chalekian Mr. Steven J. Grace Ciciora Mr. Nancy Ciesla Mr. Mary Clark Mr. Elizabeth Clawson Mr. Mary Ellen Clish Mr. Linda Cole Mr. Dana Collins Mr. Mary Comstock Mrs. Carol Conneen Mr. Diane Conrad Mr. Kathleen Conzen Mrs. Mary Cook Mr. Terry Coppenbarger Mr. Robert P. Pamela Coster Mrs. Eileen Coverick Mr. William Craine Mr.
Mary Ann Cronin Mr. Debbie Crowley Mr. Carole Cudnowski Mr. Tom Dalsanto Mr. Mary Daumen Mr. Judith Davies Ms. Courtney Davis Mr. Barbara De Waard Mr. Cindi Demlow Mr. Levester Denham, Jr. Georgia DeVitto Ms. Carla DeYoung Mr. Eva Diedrich Mr. Jennifer Doherty Mr. Mitchell I. Dolins Mr. David Domagala Mr. Jackie Donna Mr. Elisabeth Dorow Mr. Jean Doszak Ms. Irene Doyle Mr. Barbara Dragas Mr. Joseph E. Ellen Dutton Mr. Kathleen Dzialowy Mr. Florence Dziedzic Mr. Luke Edelbrock Mr. Lillian Edelbrock Ms.
Tammy Eich Mr. David Eichelkraut Mr. Charlotte Eichenlaub Mr. Lesley Eichten Mr. Sheri Elliott Mr. Josephine Ellis Mr. Shannon Ellis Mr. Diane Engstrom Mr. Miguel Estrada Ms. Donna R. Evans Mrs. Dawn M. Tim Fahey Ms. Barbara Fahnstrom Ms. Ruth E. Faklis Mrs. Jacqueline Falese Mr. Patricia Faletti Ms. Patricia Farraday Mr. Amy Farrell Mr. Craig Faust Mr. Tammy Faxel Mr. Deborah Russell Ms. Nedra Fears Mr. Kathleen Feifar Mr. David Feinberg Mr. Maryann Fese Mr.
John Fick Mr. Penny Filotto Ms. Eileen Fitzgerald Ms. Kathleen Fitzpatrick Mr. Lorraine Flood Mr. Carol Folisi Mrs. Nancy Follett Mr. Cindy Foran Mr. George P. Forsa Mr. Ann Forster Ms. Kathleen Fougerousse Mrs. Louise Frank Mrs. Bess E. Franklin Mr. Michelle Fregoso Mr. Dayna Friedman Mr.
Karen Frisch Sgt. Jennifer Furmaniak Mr. Brian S. Maria Gallegos Mr. Nancy Gardner Mr. Karen Garvey Mr. Sylvia Gary Mr. Evelyn Gatchel Mr. Tom Gausselin Mr. Pamela Gegenheimer Mr. Mary Ellen Genovese Mr. Therese Gerk Mr. Kathleen Ghiloni Mr. Gail Gilmore Mr. Monica Glynn Dr. Florence Goga Dr. Julie Goga Mr. Barbara Goss Ms. Georgene Gottsch Mr. Sylvain L. Goyette Mr. Bill Graal Mr. Rebirta D. Greene Ms. Solita M.
Paulette Gregory Mr. James Grisz Mr. Thomas Grogan Mr. Rita Gronemeyer Mr. Jeanne Gummerson Mr. Kathleen Hall Ms. Patricia Hallmark Mr. Diane Halstead Mr. Donna Hark Mr. Patricia Harris Mr. William W. Michael Harzcak Mr.
Gwendolyn Hatch Mr. Christopher C. Pamela Heavens Ms. Rudy Hejny Mr. Susan Hentschel Mr. Ellen Herron Mr. Valerie Hill-Steik Mr. Elizabeth Peeke Mr. Debra Hofbauer Mr. Christa Hogan Dr. Michele Hogan Ms. Mary Hollerich Mr. Roberta Honiotes Mr. Curtis, Jr. Carole Horn Mr. Barbara Horton Mr. William R. Martyn Howgill Mr. Virginia Hrpcha Mr. Joan Weidner Mr. Mary Iandolo Mr. Jeanine Ilg Dr. Linda Goldwyn Mr. Barbara Jack Mr. Michael A. Brady Jacobsen Ms. Susan K. Amy Jamnik Mr. Richard L.
Stanislaw Jarosz Mr. Cheryl Jarosz Ms. Marcia Jenkins Dr. Florence Johnson Mr. Kenneth J. Johnson Ms. Amanda Jones Mr. Diane Kacprowicz Mr. Karen Kalec Mr. Dawn Kapka Dr. Christine Kearney Mr. Regina Kelley Dr. Elizabeth Kelly Mr. Christine Kempa Ms. Stephanie Kenis Mr. Bernadette Kennealy Mr. Linda Kennedy Mr. James, Jr. Iva King Mr. Michael Kipilla Mrs. Jeffery T. Tina Klepec Mr. Catherine Knupp Mrs.
Anne W. Katherine Kong Mr. Maribeth Koopman Mrs. Lillian Korilko Mr. Janet Kosmal Dr. Jane Kostelc Mr. Patricia Kovacevich Mr. Martha Kozlowski Mr. Karla Kraemer Mr. Mary Alice Krajenta Mr. Colleen Kramer Mr. Susan Kruckman Mr. Karen Kubacki Mr.
Donella Kurcz Mr. Joseph P. Mary Kurpiel Ms. Regina Kutylo Mr. Dave LaBarre Mr. Cheryl LaCorte Mr. Saliee LaGrippe Mr. Lahey Mr. Linda Lahey Mr. Christina Lamboley Mr. Bob Landi Mr. Mara Lappin Mr. Grace Laski Dr. Keith Lavine Mr. Pamela A. Charles, Jr. Joan Lennon Mr. Ronald S. Lesiak, Jr. Mary K. Elizabeth Ligocki Ms. Ellen Long Mr. Etsuko Loughnane Mrs. Barbara H. Luciani Ms. Roberta A. Emilio Lullo Mr.
Jacqueline Lupo Mr. Gina Lutzke Mr. John Lyons Mr. Jeffrey Machay Mr. Louann Mackowiak Mr. James Maffia Ms. Helen Malinowski Mr. Mary Malone Mr. Rosemarie Malysiak Mr. Bonnie Mandell Mr. Douglass Mann Mr. Mike Manna Mr. Marion Manuel Mr. Michael Marano Mr. Steven D. Deborah Marketti Mr. Jan Markham Ms. Jennifer R. Markoff Mr.
Diana Markkos Mr. Rosemary Markun Mr. David L. Marlowe Mr. Edward N. Martin Mr. Nancy Martynus Dr. Kathleen Masters Ms. Susie S. Sheila Matusiewicz Mr. Peter A. Lori McAleavy Mr. Ann Marie McAuliffe Ms. Kathy McDonough Mr. Amy McDonough Mr. Jayne McDougall Mr. Laurie McElligott Mr. Norma McFadden Mr. Marty McGinnis Mr. Molly McGuire Mr. Kristine McGuire Ms. Kathleen McKee Mr. Edith McLarney Mr. Sebastian K. Edward J. Leslie M. Gina Metelica Mr. Kathleen Miller Mr. Mary Miller Mr. Anna Miller Dr.
Stephanie Millsaps Mrs. Lynn A. Minarich Mr. Winifred Mingery Mr. Maureen Mitacek Mr. Abdul Mohammed Mr. Dave Moll Mr. Mary Monaco Mr. David W. Mary Morgan Dr. Ruth Morimoto Mr. Betty Morris Mr. George Morris Mr. Christine Moskal Mr. Janice Mount Brother Donald C. Mouton, FSC Mr. Pamela Mower Mr. Kathy Muesenfechter Ms. Stephany Mulick Ms. Eileen Murphy Mr. Karen Murphy Mr. John W.
John Mylander Mr. Sharalyn S. Carolyn Nelson Mr. Rebecca Nelson Mr. Virginia Niemeyer Mr. Mary Nolan Mr. Mark Nordin Ms. James Norton Ms. Lisa L. Notter Mr. Edmund, Jr. Patricia Nowak Mr. Lawrence M. Steven Nowak Mr. Paulette Obradovich Mr. Denise Millsaps Mr. William A. Quiana M. Stephen J. Annemarie Onesti Mr. David Oravetz, Jr. Dennis Ott Mr.
Sue Pajak Mr. Marilyn Paladino Mr. Jon A. Panozzo Mr. Mark Parrington Ms. Jessica Parthun Mr.
Elefther Karapas-Parafink Dr. Julie Kirkeeng Mr. William Kurtis Mr. Dennis LeBlanc Ms. Laurette Liesen Mr. Mark S. Littlejohn Mr. Eveann Lovero Mr. Pamela Lutz Mr. Anne Leen Lyons Mr. Christina Maratea Mr. Sandra McGill Mr. Betty McKeown Mr. Cathleen Meegan Mr. Joan Murphy Dr. Kenneth L. Nancy Nguyen Mr. Eric Palm Mr. Margaret Palmasani Mr. Sheila Panozzo Ms. Julie Penner Mrs. Barbara Petrarca Mr. Petty IV Mr. Cheryl Powell Mr.
Bobbie Rand Mr. Susan Reiland Ms. Denise Rich Ms. Therese M. Deanna C. James J. Saya Mr. Nancy Schaefer Mr. Kathleen Scheuber Drs. Debra Shapiro Mr. Gwen Shaw Mr. Leslie Sims Mrs. Johnni M. Joseph M. Judith Skodon Mr.
William Slabich, Jr. Susan Stenvog Mr. Debbie Strahanoski Mr. Brian, Sr. Elizabeth Summers Mr. Ashley Swiercz Mr. Kyle Trippeer Mr. Scott Trost Mr. Susan Troy Mr. Kevin Twomey Mr. Denise Vanderwoude Mr. Mark Vieha Dr. Kurt Wagner Mr. Carol Wassberg Mr. Theresa Weitendorf Mr. Carol White Mr. Moses Williams, Jr.
Buck Services, Inc. Kozol Brothers, INC. Krull Window Company, Inc. Murer Consultants, Inc. Victor F. Splitt Insurance Wm. Wrigley Jr. Karen R. Joy Alexander Mr. Matthew T. Jean Balsamo Ms. Jaime L. Teri Bannon Ms. Sandra M. Barutha Mr. Patricia Bates Mr. Charlene Bermele Mrs. Lisa Brauer Mr. Dan Breier Mr. Philip P. Gloria Brinkman Mr. Joseph Brosnan Mr. Patricia Buchar Dr. Lillian Buckley Mr. David Buddle Mr. Mary Canaday Ms. Laura Carbaugh Mr. Traci Cassell Mr. Jason Cavanagh Mr.
Susan Ceplecha Mr. Rita Cerne Mr. Nan Chignoli Dr. Joanna Chura Mr. Lynne Corrao Mr. Sandra Cowgill Mr. Stephen Crady Dr. Rebecca Cremin Mr. Maureen Culleeney Dr. Robert A. Joyce Davis Mr. Frank DeGrassi Mr. Drew Diskin Mr. John Doyle Mr. Durkin Mr. Edna Dziak Mr. Ellen Feeney Mr. Barbara Ficarello Mr. Robert, Sr. Barbara Finley Dr. Kathleen Fitzgerald Ms. Susan Flick Mr. Amy Freelove Mr. Nancy Futterer Mr. Charles R. Eric M. Mary Gestrich Mr.
Joan Gillespie Drs. Charlene Glowaty Mr. Lisa Gregg Mr. Michelle Greuling Mr. Rosalie Guliford Mr. William B. Barbara Gutierrez Mr. LuAnn Hall Mr. Neal Hallahan Ms. Martin C. Judy Hicks Mr. Rodger Horst Mr. Antonetta Huber Mr. Pamela Hynes Mr. Robert Iles Mrs. Jeanne Jacobs Mr.
Mary Janc Mr. Pamela Jastczemski Dr. Pamela Jessee Dr. Lawrence Jochum Mr. Cindy Johnson Mrs. Julie M. Lawrence Kaffel Mr. Patricia Kanellakes Ms. Joanne Kantner Ms. Frank, Jr. Ann Kavanaugh Dr. Jerry Kavouras Mr.
Ellen Kehoe Mr. Alexis Nazario Mr. Marcia Kezerle Dr. Virginia Klemic Dr. Elizabeth Kozak Dr. Kathleen Kozminski Mr. Marianne Kraft Dr. Julie Krahl Mrs. Holly Lamb Ms. Ramona LaMontagne Mr. Paul B. Langos Mr. Karen Lansky Dr. Mary Lou Larson Dr. Nellie Lawson Dr. Susan Lee Mr. Mildred Lehnert Mr. John, Sr. Patricia Lenz Mr. Patricia Linck Mrs. Cheryl Lingle Mr. Ruth Longman Mr. Kaye Looney Ms.
Judi Lotter Mr. John E. Lynne Lichtenauer Mr. Susan Lyons Dr. Jean Lytle Ms. Norine Maloney Mr. Therese Manderino Mr. Marian Marinari Mr. Frank Marsaglia Mr. Pamela Martyn-Nemeth Mr. Gregory M. Brad McFaul Mr. Mickey McKee Mr. Julie McKune Drs. Peter McMenamin Mrs. Valerie Meaney Mr.
Tracy Mikalauski Mr. Brad Miller Mr. James Montanari Mr. Diane Morefield Mr. Lorraine Morrey Dr. Margaret Moses Mr. James, USN Ret. Catherine Munsterman Mr. Thomas Murphy Mr. Marianne Nelsen Mr. David Nelson Mr. Marilyn Nelson Mr. Amanda Nichols Ms. Melanie Obispo-Young Mr. Kim Pacholski Mr. Jean Palm Mr. Paul Palmer Ms. Kimberly Perona Mr. Joseph Petrosko, Jr. Susan Peyla Mrs. Joanne A. Porazinski Mr.
Patricia Pratapas Ms. Peggy Pratl Reverend Richard B. Prodehl Mr. Richard, Jr. Angela Reed Ms. Barbara M. Reidy Mr. Mary Reilly Professor Ellen T. Jennifer Rigley Ms. Judith Rollins Mrs. Meredith Rose Mr. Rita Ruddy Mr.
Deena Rush Mr. Constance Russell Mr. Laurie Ryan Mr. Eileen Schackmuth Mr. Barbara Schwartz Mr. Margaret Sepsey Mr. Rita Sexton Mr. Lorelee Smith Mr. James M. Edmond A. Rosemary Stephen Mr. John D. Doris Szczepaniak Mr. Mary Elizabeth Tallon Dr. Marilyn Tarizzo Mr. Ellen Taylor Mr. Robert Jr. Inez Thayer Mr. Rose Thomas Mr. Pamela Thomas Mr. Barbara Thompson Ms. Lynn Tovar Mr. Derek Tresnak Mr.
Karen Tyler Dr. Nancy Vahl Mr. Valerie Vander Vliet Mr. Frank A. Beverly Voyce Mr. Rosemary Wagner Mr. Suzanne Wielgos Mr. Mary Williams Mr. Susan Wolfram Mr. Nancy Workman Mr. Elizabeth Wroblewski Mr. Jion Liou Yen Mr. Brett Zbikowski Mr. Volleyball, Inc. National Seed Co. Next Media Operating Inc. Mary Adams Dr. Glenna Adamson Mr. Ester Adomako Mrs. Lori Althoff Mr. Cheryl Alton Mr. Marylin Anderson Mrs. Cynthia Andres Mrs. Karen Applehoff Mr. Sheila Arends Mr.
Lawrence Avila Mr. Ana Ayala Mr. Mary Ayer Mr. Jeff E. Balser Mr. Carolyn Bartelt Mr. Jo Barton Mr. Edward Batis Ms. Sandra Beal Ms. Sarah M. Wossenyelesh Gugsa Mr. Janice Beneveti Mr. Jackie Benoit Mr. Karen Berta Mrs.
Barbara Bertino Mr. Jon Bertino Mr. Christine Biedron Mr. Bernadette Bilder Mr. Kathleen Bilich Mr. Judith Billich Mr. Patricia Biscardi Mr. Lisa Bisgard Mr. Kathryn Bishop Mr. Sheryl Bixler Mr. Katherine Blackburn Mr. Siri Blake Mr. Patti Block Mr. Joan Bodden Mr. Ronald Boehm 16 Mr. Darius Bolling Mr.
Lillian Borse Mr. Marie Bosley Mr. John R. Bradley Mr. Regina Brett Mr. Lyndean Brick Mr. Judy Briesch Mr. Daniela Broderick Mr. John Brom Ms. Sarah Bromberek Mr. Phillip Brooks Mr. Patrick A. Doris Brozik Ms. Jenna M. Michael R. Judith C. Al Bucci Mr. Gina Buck Mr. George T. Bullock Mr. Lucy Burke Mr. David Burkhart Ms. Mary J. Burns Mr. Laura Butkovic Ms. Jane Cain Mr. Nadine Caldwell Mr. Ann Cale Mrs. Debra M. Susan Calvert Mr. Jennifer Campagna Mr.
Ryan P. Louise Canterbury Mr. Mary Capouch Mr. Loretta Capouch Mr. Mary Kay Cappitelli Mr. Lee Ann Cardwell Mr. Lisa Carey Mr. Louise Caridine Mr. Christine M. Christine Catena Mr. Loretta Cernugel Mr. Kathy Chalekian Mr. Steven J. Grace Ciciora Mr. Nancy Ciesla Mr. Mary Clark Mr. Elizabeth Clawson Mr. Mary Ellen Clish Mr. Linda Cole Mr.
Dana Collins Mr. Mary Comstock Mrs. Carol Conneen Mr. Diane Conrad Mr. Kathleen Conzen Mrs. Mary Cook Mr. Terry Coppenbarger Mr. Robert P. Pamela Coster Mrs. Eileen Coverick Mr. William Craine Mr. Mary Ann Cronin Mr. Debbie Crowley Mr. Carole Cudnowski Mr. Tom Dalsanto Mr. Mary Daumen Mr.
Judith Davies Ms. Courtney Davis Mr. Barbara De Waard Mr. Cindi Demlow Mr. Levester Denham, Jr. Georgia DeVitto Ms. Carla DeYoung Mr. Eva Diedrich Mr. Jennifer Doherty Mr. Mitchell I. Dolins Mr. David Domagala Mr. Jackie Donna Mr. Elisabeth Dorow Mr.
Jean Doszak Ms. Irene Doyle Mr. Barbara Dragas Mr. Joseph E. Ellen Dutton Mr. Kathleen Dzialowy Mr. Florence Dziedzic Mr. Luke Edelbrock Mr. Lillian Edelbrock Ms. Tammy Eich Mr. David Eichelkraut Mr. Charlotte Eichenlaub Mr. Lesley Eichten Mr. Sheri Elliott Mr. Josephine Ellis Mr. Shannon Ellis Mr. Diane Engstrom Mr. Miguel Estrada Ms.
Donna R. Evans Mrs. Dawn M. Tim Fahey Ms. Barbara Fahnstrom Ms. Ruth E. Faklis Mrs. Jacqueline Falese Mr. Patricia Faletti Ms. Patricia Farraday Mr. Amy Farrell Mr. Craig Faust Mr. Tammy Faxel Mr. Deborah Russell Ms. Nedra Fears Mr. Kathleen Feifar Mr. David Feinberg Mr. Maryann Fese Mr. John Fick Mr.
Penny Filotto Ms. Eileen Fitzgerald Ms. Kathleen Fitzpatrick Mr. Lorraine Flood Mr. Carol Folisi Mrs. Nancy Follett Mr. Cindy Foran Mr. George P. Forsa Mr. Ann Forster Ms. Kathleen Fougerousse Mrs. Louise Frank Mrs. Bess E. Franklin Mr. Michelle Fregoso Mr. Dayna Friedman Mr. Karen Frisch Sgt. Jennifer Furmaniak Mr.
Brian S. Maria Gallegos Mr. Nancy Gardner Mr. Karen Garvey Mr. Sylvia Gary Mr. Evelyn Gatchel Mr. Tom Gausselin Mr. Pamela Gegenheimer Mr. Mary Ellen Genovese Mr. Therese Gerk Mr. Kathleen Ghiloni Mr. Gail Gilmore Mr. Monica Glynn Dr. Florence Goga Dr. Julie Goga Mr. Barbara Goss Ms. Georgene Gottsch Mr. Sylvain L. Goyette Mr. Bill Graal Mr. Rebirta D. Greene Ms. Solita M. Paulette Gregory Mr. James Grisz Mr. Thomas Grogan Mr.
Rita Gronemeyer Mr. Jeanne Gummerson Mr. Kathleen Hall Ms. Patricia Hallmark Mr. Diane Halstead Mr. Donna Hark Mr. Patricia Harris Mr. William W. Michael Harzcak Mr. Gwendolyn Hatch Mr. Christopher C. Pamela Heavens Ms. Rudy Hejny Mr. Susan Hentschel Mr. Ellen Herron Mr. Valerie Hill-Steik Mr. Elizabeth Peeke Mr. Debra Hofbauer Mr. Christa Hogan Dr. Michele Hogan Ms. Mary Hollerich Mr. Roberta Honiotes Mr. Curtis, Jr. Carole Horn Mr.
Barbara Horton Mr. William R. Martyn Howgill Mr. Virginia Hrpcha Mr. Joan Weidner Mr. Mary Iandolo Mr. Jeanine Ilg Dr. Linda Goldwyn Mr. Barbara Jack Mr. Michael A. Brady Jacobsen Ms. Susan K. Amy Jamnik Mr. Richard L. Stanislaw Jarosz Mr. Cheryl Jarosz Ms. Marcia Jenkins Dr. Florence Johnson Mr. Kenneth J. Johnson Ms. Amanda Jones Mr. Diane Kacprowicz Mr.
Karen Kalec Mr. Dawn Kapka Dr. Tools for Data Analysis. Astronomy Paper. Effective Practices in Educational Technology. Effective technological methods and teaching practices adopted to successfully complete the calculus based physics II course in remote method. General Relativity in the High School Classroom. High School. Neutrino Physics in the Classroom. Per Curriculum and Instruction II.
Tools for Teaching Computation in Physics. Creating interdisciplinary pathways into quantum careers: opportunities for physics departments. Transforming Physics Curricula to Include Computation. Computational Thinking in Physics.
Communicating Sensitive Topics in the Classroom. Frontiers of Astronomy. Innovations in Teaching Space Science and Astronomy. Introductory Courses II. Evaluating the uptake of research-based instructional strategies in physics, math and chemistry. Teaching Equity in Physics. The Art and Science of Teaching.
Early Career Topical Discussion.
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